“Strong” = several concordant meta-analyses or systematic reviews. “Moderate” = one synthesis, or several controlled trials. “Limited” = early trials only. The rating is about the quality of the studies, not about how useful the supplement is.
It has become a social media sensation. Its effect on blood sugar levels after a meal is real and has been measured; as for the weight-loss claims, however, they are based on just one trial.
In patients with type 1 diabetes suffering from gastroparesis, 30 ml of apple cider vinegar significantly slowed gastric emptying — which may hinder rather than help their blood sugar control. Medical advice is required for those with treated diabetes, as vinegar also affects blood sugar levels. It is also worth noting that when vinegar curbs the appetite, it is largely because it is unpleasant to drink. The reduction in appetite observed in healthy adults was accompanied by a significant increase in nausea, which was all the more pronounced as the preparation was considered unappetising. With regard to weight, only one trial yielded a clearly positive result; another, involving eight weeks of daily vinegar intake in adults at metabolic risk, improved blood sugar levels and insulin levels without affecting body fat. A 2020 systematic review concluded that the quality of the available research was insufficient to draw any conclusions. As for the topical applications popularised online: diluted vinegar baths did not improve either the integrity of the skin barrier or the skin microbiome in atopic dermatitis, with most participants also reporting irritation.
In clinical trials, 15 to 30 ml per day was used, taken with meals. As regards the effect on post-prandial blood glucose levels, a small amount in a salad dressing proved sufficient in healthy subjects: it is the acidity that has the effect, not the dose.
Although it improves blood glucose control, red wine vinegar consumed daily for 8 weeks did not result in a significant reduction in adiposity (body fat, weight, BMI or waist circumference).
A systematic review and meta-analysis of randomised clinical trials evaluated the effect of apple cider vinegar (ACV) on blood lipids and glycaemic parameters in adults. ACV consumption significantly decreased total cholesterol, fasting blood glucose, and HbA1C. However, no significant effect was found on LDL cholesterol, HDL cholesterol, fasting insulin, or HOMA-IR.
Hadi A, Pourmasoumi M, Najafgholizadeh A, Clark CCT, Esmaillzadeh A. — BMC complementary medicine and therapies (2021) — View the source study
For information only: not a substitute for medical advice. Dietary supplements are not a replacement for a varied, balanced diet. Learn more