“Strong” = several concordant meta-analyses or systematic reviews. “Moderate” = one synthesis, or several controlled trials. “Limited” = early trials only. The rating is about the quality of the studies, not about how useful the supplement is.
Wheat bran makes stools heavier and accelerates slow transit: this is its best-established effect. Against irritable bowel syndrome, constipation in hospital or colon polyps, trials are disappointing.
HDL: in healthy young men, HDL-cholesterol (the "good" one) dropped even more than total cholesterol. Tolerance: in 188 patients with irritable bowel syndrome, wheat bran was less well tolerated than partially hydrolyzed guar gum; in another trial, oat fiber tablets produced fewer side effects. Limitations: irritable bowel syndrome: in 59 patients, 30 g per day did not do better than the control group (52% improvement against 65%); compared to partially hydrolyzed guar gum, 40% success against 60%. Constipation: the meta-analysis considers it only partially effective in restoring normal transit in constipated individuals. Colon polyps: in a randomized trial on wheat bran fiber, the supplement did not reduce their recurrence. Neither stress, mood, nor other measured health markers changed in two recent trials (55 g per day of extruded bran, 20 g of finely ground bran). Trials are often old and small (5 to 69 participants for the most part).
In trials: 20 to 30 g of wheat bran per day, up to 40 g.
Wheat bran regulates transit in both directions: in 18 students and 10 adults, about 20 g per day accelerated slow transits, but slowed down those that were fast to begin with.
This randomized, triple-blind, placebo-controlled trial evaluated the effects of 55 g of extruded wheat bran per day on the psychobiological functions of 69 healthy men. The consumption of extruded wheat bran increased serum acetate and butyrate. However, the intervention did not modulate psychobiological functions, such as stress response or mood, nor secondary gut health measures.
Dalile B, La Torre D, Kalc P, Zoppas F, Roye C, Loret C, Lamothe L, Bergonzelli G, Courtin CM, Vervliet B, Oudenhove LV, Verbeke K. — Frontiers in nutrition (2022) — View the source study
For information only: not a substitute for medical advice. Dietary supplements are not a replacement for a varied, balanced diet. Learn more