“Strong” = several concordant meta-analyses or systematic reviews. “Moderate” = one synthesis, or several controlled trials. “Limited” = early trials only. The rating is about the quality of the studies, not about how useful the supplement is.
Taken 3 to 6 days before exercise, sodium phosphate improved VO2max and time trial performance in small trials. More recent time trial trials show no effect.
Tolerance: the study summaries in this profile do not describe adverse effects, and the loading phases last only a few days: nothing on prolonged intake. Limitations: time trials: nothing over 20 km (20 cyclists), over 30 km (16 cyclists), nor in 100 and 250 kJ events, 1 or 8 days after loading. In female cyclists, neither 25, 50, nor 75 mg/kg per day improved the time trial. In hypoxia: no aerobic capacity gain in 24 cyclists, only 3 to 5% in a few responders. In trained athletes, 6 days of loading changed neither VO2peak nor energy intake; a commercial product changed neither endurance nor power in 11 men. In eleven team sport players, the gain on repeated sprints was not significant. Reviews consider the results inconsistent (dose, type of effort, fitness level of athletes).
50 mg per kg of lean mass per day (or 1 g four times a day), for 3 to 6 days before the event.
In 7 runners, VO2max increased significantly after 6 days of sodium phosphate, but their 5-mile time did not change significantly.
This study examined the effects of a 6-day sodium phosphate supplementation (50 mg/kg of fat-free mass/day) on aerobic capacity in hypoxia in 24 trained male cyclists. Overall, aerobic capacity in hypoxia was not improved by supplementation. However, high individual variability was observed, with certain individuals (responders) showing a 3% to 5% increase in performance. The study concludes that sodium phosphate is not a generalized ergogenic aid for aerobic capacity in hypoxia, but could benefit certain athletes.
Płoszczyca K, Chalimoniuk M, Przybylska I, Czuba M. — Nutrients (2022) — View the source study
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