“Strong” = several concordant meta-analyses or systematic reviews. “Moderate” = one synthesis, or several controlled trials. “Limited” = early trials only. The rating is about the quality of the studies, not about how useful the supplement is.
Soluble fiber extracted from acacia sap. At 10 g per day, it feeds good gut bacteria and made stools more frequent in irritable bowel syndrome; its effects on weight and blood sugar remain small and poorly studied.
Digestion: at 40 g in a single dose, bloating, gas, and gurgling were more frequent than with placebo, even though discomfort remained low; at 30 g per day, nausea and loose stools the first week. Kidney disease: in kidney failure patients, 10 to 40 g per day slightly lowered blood sodium (from 138 to 136 mmol/L). Lean mass: in the 12-week trial on metabolic syndrome, lean mass dropped in the gum arabic group, who also ate less. Limits: few trials: the meta-analysis includes only 6 short trials, and its authors ask for results to be taken with caution, especially for blood sugar. Without placebo: trials on rheumatoid arthritis (40 patients) and sickle cell disease (47 patients), which report less inflammation, oxidative stress, and cholesterol, lacked a placebo group. Cholesterol: the 25.9% cholesterol drop comes from a non-randomized trial where the gum was added to atorvastatin; HDL did not budge in this trial or in sickle cell patients. Kidney: a trial on 30 kidney failure patients found no drop in urea or creatinine, and the hope of avoiding dialysis in children rests on two children.
10 g per day for the microbiota and irritable bowel syndrome; 20 to 30 g per day in trials on blood pressure, weight, and diabetes.
At 10 g per day for 4 weeks, gum arabic increased stool bifidobacteria and lactobacilli more than the same dose of inulin, the reference prebiotic.
This systematic review and meta-analysis of randomized clinical trials in adults examined the effects of oral gum arabic supplementation. The results suggest that gum arabic can contribute to a significant reduction in body mass index (BMI), weight, and fasting blood glucose. These effects could position gum arabic as a promising nutritional intervention for managing cardiometabolic risk factors and weight loss in adults.
Jumaa MA, Budh DP, Nazir Q, Rahman MJ, Radix C. — Journal of diabetes and metabolic disorders (2026) — View the source study
For information only: not a substitute for medical advice. Dietary supplements are not a replacement for a varied, balanced diet. Learn more