“Strong” = several concordant meta-analyses or systematic reviews. “Moderate” = one synthesis, or several controlled trials. “Limited” = early trials only. The rating is about the quality of the studies, not about how useful the supplement is.
Eaten alone, peanuts change neither weight, blood pressure, nor LDL in trials; they raise HDL slightly. Links to less diabetes and death come from observational studies.
Allergy: peanuts can cause an allergy. In 640 at-risk infants (severe eczema or egg allergy), peanut allergy at age 5 affected 13.7% of those who avoided them versus 1.9% of those who ate them early: early introduction was done after a skin test, as part of a supervised trial. If your child is at risk, seek medical advice before giving them any. Weight: peanuts are not neutral for all that. In trials, 42 g per day varied in flavors caused a gain of 0.9 kg, and as a pre-load before dinner, a cereal bar caused more weight loss than peanuts (−1.3 vs −0.2 kg in 8 weeks). Limitations: heart: in the meta-analysis of 13 trials on peanuts alone, no significant effect on weight, waist circumference, blood pressure, LDL, triglycerides, total cholesterol, or fasting blood glucose. The drops in LDL and total cholesterol from meta-analyses combining peanuts and tree nuts have "very low" certainty. Blood pressure: out of 21 trials on tree nuts and peanuts, only pistachios and nut mixes lowered blood pressure significantly. Inflammation: in 64 overweight men, 56 g per day of peanuts, conventional or high-oleic, for 4 weeks changed neither inflammation markers nor oxidative stress; a meta-analysis of 20 studies finds no effect of nuts on CRP. Observation only: the link with less diabetes and death comes from cohorts, which do not prove that peanuts are the cause; in the meta-analysis on cancer, cancer mortality was 8% lower in the highest peanut consumers.
25 to 56 g per day of peanuts, or 32 g of peanut butter, for 4 weeks to 6 months in trials.
Two weeks of overeating, with the same calorie surplus: the sweet group gained weight and waist circumference, the peanut group did not, and its LDL was lower at the end of the trial (2.1 vs 2.6 mmol/L).
This systematic review and meta-analysis, including 27 studies and 1,121 participants, examined the effect of consuming tree nuts and peanuts on intake, compensation, and energy expenditure. It found energy compensation after peanut consumption, which could explain the lack of weight gain. Conversely, no evidence was found that peanuts increase energy expenditure.
Nikodijevic CJ, Probst YC, Tan SY, Neale EP. — Advances in nutrition (Bethesda, Md.) (2023) — View the source study
For information only: not a substitute for medical advice. Dietary supplements are not a replacement for a varied, balanced diet. Learn more