“Strong” = several concordant meta-analyses or systematic reviews. “Moderate” = one synthesis, or several controlled trials. “Limited” = early trials only. The rating is about the quality of the studies, not about how useful the supplement is.
Slightly lowers LDL cholesterol, blood sugar and blood pressure; almost nothing on weight, and a real risk to the liver at high doses in capsules.
The liver first. EFSA notes rare cases of liver damage with supplements, and rising transaminases in trials starting from 800 mg of EGCG per day. In the largest trial, 843 mg of EGCG per day for one year in 1,075 postmenopausal women, 6.7% had elevated ALT (a liver enzyme), including 1.3% severely, along with more nausea and skin reactions. Out of 1,414 patients with supplement- or medication-related liver injuries, 40 cases were attributed to green tea, often severe, sometimes leading to transplantation, and linked to a gene (HLA-B*35:01) suggesting an individual-specific reaction. The US Pharmacopeia review recorded 216 reports, including 34 liver damages, more frequent with a concentrated extract taken on an empty stomach; one case of acute liver failure has also been published. The trial finding weight loss used 856.8 mg of EGCG per day, above EFSA's 800 mg threshold. Limitations: on weight, the Cochrane review finds a small, clinically insignificant loss and no effect on weight maintenance; another meta-analysis mentions a small effect. The effect on fat utilization at rest and during exercise is deemed inconclusive by one review. The effects on blood sugar partly come from at-risk individuals, such as the trial in 60 volunteers with borderline diabetes.
456 to 625 mg of catechins per day in two trials; in capsules, no more than 338 mg of EGCG per day (level deemed safe)
In 10 men, a green tea extract increased 24-hour energy expenditure by 4%, more than caffeine alone.
This meta-analysis of 13 randomized controlled trials evaluated the effect of green tea consumption on blood pressure and other parameters. It showed a significant reduction in systolic blood pressure (-2.08 mmHg) and diastolic blood pressure (-1.71 mmHg). In addition, significant decreases in total cholesterol and LDL cholesterol were observed. The effects on blood pressure appeared more pronounced in participants with systolic pressure greater than or equal to 130 mmHg and when consuming green tea extracts.
Khalesi S, Sun J, Buys N, Jamshidi A, Nikbakht-Nasrabadi E, Khosravi-Boroujeni H. — European journal of nutrition (2014) — View the source study
For information only: not a substitute for medical advice. Dietary supplements are not a replacement for a varied, balanced diet. Learn more